Background: Care for families affected by Familial Breast and Ovarian Cancer (FBOC) is challenging as a broad range of professions and specialties are involved. The aim was to review management and outcomes for a cohort of women at high risk for familial breast and ovarian cancer. Methods: Ten-year retrospective follow-up study of individuals in Southern New Zealand assessed by Genetic Health Service New Zealand to be high risk for FBOC and without a personal cancer diagnosis at time of consultation. Results: Twenty women were identified; twelve underwent genetic testing, and a pathogenic BRCA variant was identified in eleven. Eight women had no testing, as no index case was available. Guidelines had been fully adhered to in 55% of women, regardless of BRCA status. Six did not undergo appropriate breast surveillance. To date, seven of the 11 patients who tested positive for a pathogenic BRCA variant (64%) had risk-reducing surgeries. Two women were diagnosed with breast cancer on surveillance imaging; none were diagnosed with ovarian cancer. Four women were lost to follow-up, one of whom subsequently presented with a symptomatic breast cancer. Conclusions: To our knowledge, this is the first study providing long-term data for FBOC in New Zealand. Overall, guidelines were followed satisfactorily, but some women did not receive appropriate surveillance or referrals. An integrated interdisciplinary long-term care provision model in New Zealand might help to address gaps in FBOC surveillance and management.
Petrich, S., McKergow, E., Bawden, S., & Sullivan, J. (2024). Ten-Year Follow-Up of Women at High Risk for Familial Breast and Ovarian Cancer in Otago and Southland, New Zealand. Asian Pacific Journal of Cancer Prevention, 25(1), 3-7. doi: 10.31557/APJCP.2024.25.1.3
MLA
Simone Petrich; Erin McKergow; Suzannah Bawden; Jan Sullivan. "Ten-Year Follow-Up of Women at High Risk for Familial Breast and Ovarian Cancer in Otago and Southland, New Zealand". Asian Pacific Journal of Cancer Prevention, 25, 1, 2024, 3-7. doi: 10.31557/APJCP.2024.25.1.3
HARVARD
Petrich, S., McKergow, E., Bawden, S., Sullivan, J. (2024). 'Ten-Year Follow-Up of Women at High Risk for Familial Breast and Ovarian Cancer in Otago and Southland, New Zealand', Asian Pacific Journal of Cancer Prevention, 25(1), pp. 3-7. doi: 10.31557/APJCP.2024.25.1.3
VANCOUVER
Petrich, S., McKergow, E., Bawden, S., Sullivan, J. Ten-Year Follow-Up of Women at High Risk for Familial Breast and Ovarian Cancer in Otago and Southland, New Zealand. Asian Pacific Journal of Cancer Prevention, 2024; 25(1): 3-7. doi: 10.31557/APJCP.2024.25.1.3
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