Cancer Incidence Relation to Heavy Metals in Soils of Kyzylorda Region of Kazakhstan

Rakhimbekova, Farida; Kaidarova, Dilyara R.; Orazgalieva, Madina; Ryspambetov, Zhassulan; Buzdin, Anton; Anapiyayev, Bakytzhan

doi:10.31557/APJCP.2024.25.6.1987

Cancer Incidence Relation to Heavy Metals in Soils of Kyzylorda Region of Kazakhstan

Document Type : Research Articles

Authors

¹ Chemical Processes and Industrial Ecology Department, Mining and Metallurgical Institute named after O.A. Baikonurov, Satbayev University, Almaty, 050013, Kazakhstan.

² Kazakh National Research Institute of Oncology and Radiology, Kazakhstan.

³ Kyzylorda Regional Cancer Center, Kazakhstan.

⁴ Department of Genomics and Postgenomic Technologies, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Federation.

⁵ Chemical and Biochemical Engineering Department, Geology and Oil-gas Business Institute named after K.Turyssov, Satbayev University, Kazakhstan.

10.31557/APJCP.2024.25.6.1987

Abstract

Objective: The purpose of this study was to investigate the relationship of soil pollution factors such as heavy metal ions with the incidence of cancer in the Kyzylorda region of Kazakhstan. Methods: Concentrations of heavy metal ions in the soils of different sites of Kyzylorda region, Kazakhstan, were sampled and correlated with incidence of cancer in 2021. Results: Chromium content in the soil exceeded maximum permissible concentration (MPC) in the samples for all sites except Kazaly and Shieli, and the highest excess of 2.8 MPC was found in Terenozek. Content of copper, lead, and cobalt ions was also increased and varied in the range 1.9-15.4, 1.2-4, and 1.2-2.44 MPC, respectively. In addition, lung cancer incidence was statistically significantly correlated with soil concentration to MPC ratio of copper, cobalt, and lead; colorectal cancer was correlated with soil concentration of chromium. Cases of invasive cancer and mutations were recorded Terenozek and Kyzylorda areas. Conclusion: The higher the soil concentration correlate with higher cancer incidence in Kyzylorda region, Kazakhstan.

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