Comparison of Pain, Cortisol, and IL6 Levels Pre and Post SEFT in Stage III B Cervical Cancer Patients

Document Type : Research Articles

Authors

1 Department of Midwifery, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Jakarta, Indonesia.

2 Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

3 Department of Anesthesiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

4 Department of Surgical Sciences, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

5 Department of Physiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

6 Department of Clinical Nutrition, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

7 Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia.

8 Department of Microbiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

9 Department of Nutrition, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Jakarta, Indonesia.

10 Department of Nursing Science, Faculty of Nursing, Universitas Muhammadiyah Jakarta, Central Jakarta, Indonesia.

Abstract

Objective: The objective of the study is to assess the impact of Spiritual Emotional Freedom Technique (SEFT) intervention on pain severity, cortisol, and IL6 levels in stage III B cervical cancer patients undergoing chemoradiation. Methods: A quasi-experimental study with a one-group pre-test post-test design was conducted at Gatot Soebroto Hospital, Jakarta, Indonesia, focusing on stage III B cervical cancer patients who received chemoradiation. Pain severity was quantified using the Numeric Rating Scale (NRS), while cortisol and IL6 levels were determined via serum specimen collection and ELISA analysis. Statistical analysis revealed significant disparities in pain severity, cortisol levels, and IL6 levels pre- and post-intervention. A significant correlation emerged between pain severity, cortisol, and IL6 levels (p<0.001). Result: The average pre-intervention pain severity was 4.5 and the average post-intervention pain severity was 1.6. The average pre-intervention cortisol level was 632.9 and the average post-intervention cortisol level was 305.3 (p-value <0.001). The average pre-intervention IL6 level was 260.1 and the average post-intervention IL6 level was 106.7. Conclusion: The SEFT proves highly effective in alleviating pain among cervical cancer patients undergoing chemoradiation.

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Asian Pacific Journal of Cancer Prevention
Volume 26, Issue 2
February 2025
Pages 625-630

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History

  • Receive Date: 09 October 2024
  • Revise Date: 27 November 2024
  • Accept Date: 16 February 2025

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