Purpose: This study aims to evaluate the impact of varying Aperture Shape Controller (ASC) settings on the optimization of VMAT plans for tongue carcinoma (Ca-Tongue), focusing on their role in modulating plan complexity, maintaining dosimetric integrity, and ensuring accurate treatment delivery. Materials and Methods: Twenty Ca-Tongue patients were retrospectively planned using four ASC settings: Off, Very Low, Moderate, and Very High, totaling 80 plans. Complexity metrics such as Modulation Complexity Score (MCSv), Small Aperture Score (SAS), and Monitor Units per cGy (MU/cGy) were computed using MATLAB from exported DICOM RT files. Each plan underwent portal dosimetry QA with gamma analysis (3%/3mm and 2%/2mm). Dosimetric quality was evaluated using Conformity Index (CI), Homogeneity Index (HI), and PTV D98%, along with doses to organs-at-risk (OARs). Statistical analysis included the Wilcoxon signed-rank test and linear regression. Results: Increasing ASC level significantly reduced plan complexity: MCSv increased from 0.32±0.02 (Off) to 0.38±0.03 (Very High), SAS decreased from 0.47±0.04 to 0.37±0.07, and MU/cGy dropped from 2.25±0.09 to 2.03±0.12 (p < 0.05). However, higher ASC levels were associated with minor but consistent reductions in PTV coverage (D98%: 96.66% to 94.94%) and increases in OAR doses (e.g., spinal cord Dmax: 30.46 Gy to 34.90 Gy). CI and HI remained clinically acceptable across all settings. Gamma pass rates were uniformly high (≥98.85%), with no significant improvement across ASC levels. Weak or negligible correlations (R² < 0.323) were found between complexity metrics and gamma outcomes. Conclusion: The ASC effectively reduces plan complexity in VMAT for Ca-Tongue without compromising delivery accuracy. While Very High ASC yields the greatest complexity reduction, it also introduces modest trade-offs in PTV coverage and OAR sparing. The Moderate ASC setting appears optimal, offering a balance between complexity control and dosimetric quality. Clinical implementation of ASC should be tailored to tumor site and anatomy, with Moderate ASC recommended for head and neck VMAT to ensure safety, efficiency, and robust QA performance.
M, A. , Show, S. , Jha, S. , Prakash, A. and S, C. (2026). A Multidimensional Assessment of the Aperture Shape Controller in VMAT for Ca Tongue: Implications for Plan Complexity and Quality Assurance. Asian Pacific Journal of Cancer Prevention, 27(2), 685-691. doi: 10.31557/APJCP.2026.27.2.685
MLA
M, A. , , Show, S. , , Jha, S. , , Prakash, A. , and S, C. . "A Multidimensional Assessment of the Aperture Shape Controller in VMAT for Ca Tongue: Implications for Plan Complexity and Quality Assurance", Asian Pacific Journal of Cancer Prevention, 27, 2, 2026, 685-691. doi: 10.31557/APJCP.2026.27.2.685
HARVARD
M, A., Show, S., Jha, S., Prakash, A., S, C. (2026). 'A Multidimensional Assessment of the Aperture Shape Controller in VMAT for Ca Tongue: Implications for Plan Complexity and Quality Assurance', Asian Pacific Journal of Cancer Prevention, 27(2), pp. 685-691. doi: 10.31557/APJCP.2026.27.2.685
CHICAGO
A. M , S. Show , S. Jha , A. Prakash and C. S, "A Multidimensional Assessment of the Aperture Shape Controller in VMAT for Ca Tongue: Implications for Plan Complexity and Quality Assurance," Asian Pacific Journal of Cancer Prevention, 27 2 (2026): 685-691, doi: 10.31557/APJCP.2026.27.2.685
VANCOUVER
M, A., Show, S., Jha, S., Prakash, A., S, C. A Multidimensional Assessment of the Aperture Shape Controller in VMAT for Ca Tongue: Implications for Plan Complexity and Quality Assurance. Asian Pacific Journal of Cancer Prevention, 2026; 27(2): 685-691. doi: 10.31557/APJCP.2026.27.2.685
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