Identification and GenBank Registration of Two Novel Bloodstream Bacterial Strains from Oncology Patients: Escherichia Coli OncoEval 1 and Pseudomonas Aeruginosa OncoEval 2

Document Type : Short Communications

Authors

1 Faculty of Pharmacy, Al Rafidain University, 10001, Baghdad, Iraq.

2 Department of Pharmacology and Life Sciences, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia.

3 School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Subang Jaya, Selangor, Malaysia.

4 Medical Oncology Department, Oncology Teaching Hospital Baghdad, Baghdad, Iraq.

5 Department of Haematology, Medical city complex, Haematology and Transplant centre, Baghdad, Iraq.

6 Department of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia.

7 Medical Oncology Department, Alamal National Hospital for Cancer Treatment, Baghdad, Iraq.

Abstract

Objective: Bloodstream infections are a significant complication in cancer patients and play an important role in morbidity and mortality, especially in immunocompromised populations. It is crucial that clinically derived bacterial strains be molecularly documented to aid infection surveillance and future translational research in oncology practice. Methods: This brief communication describes the identification and National Center for Biotechnology Information (NCBI) GenBank registration of two bacterial strains isolated from bloodstream infections in oncology patients. Partial 16S ribosomal RNA gene sequencing was used for molecular identification. Results: One isolate was identified as Escherichia coli strain OncoEval 1, and the second as Pseudomonas aeruginosa strain OncoEval 2. Validated and quality-screened sequences of both were deposited in the GenBank database to provide public genomic references derived from cancer-associated bloodstream infections. Conclusion: The registration of these strains broadens the molecular resource base for pathogens isolated from oncology patients and drives continued studies in infection surveillance and research in the setting of cancer care.

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