The Effect of Exercise on Quality of Life among Patients and Survivors of Breast Cancer: A Systematic Review and Meta-Analysis

Document Type : Systematic Review and Meta-analysis

Authors

1 Department of Community Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana (Ambala), India.

2 Department of Otorhinolaryngology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana (Ambala), India.

3 Department of General Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, India.

4 Department of Anaesthesia, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana (Ambala), India.

Abstract

Introduction: The impact of physical activity on the quality of life in breast cancer patients and survivors is examined in this study by a comprehensive meta-analysis of randomized control trials. Materials and procedures: We searched databases like PubMed, Scopus, Embase, and Google Scholar for research publications published between 2005 and 2024, using the PRISMA guidelines. R software was utilised to perform the meta-analysis, and Cochrane’s ROB 2.0 tool was employed to assess the quality of the studies. We utilised the I2 statistics to evaluate heterogeneity. A funnel plot and Egger’s regression test were used to determine publication bias. Results: The pooled effect of training on overall health-related quality of life (HRQOL) in survivors and patients of breast cancer was estimated to have been 0.70 (CI = 95%: 0.41–0.99) using a random effects model. HRQOL was calculated using Functional Assessment of Cancer Therapy-Breast (FACT-B) outcomes in breast cancer survivors and patients with cancer following giving them physical training and fitness intervention. The downward trend in the meta-regression study suggests that younger people benefited more from exercise in terms of quality of life than older patients. Participants in Asia [1.72 (CI = 95%: -0.60-4.05)], America [0.52 (CI = 95%: 0.30-0.74)], and Australia [0.43 (CI = 95%: 0.24-0.61)] had a stronger effect of the treatment compared to patients in Europe [0.51 (CI = 95%: -0.12-1.15)], according to sub-group analysis. Conclusion: Physical activity enhances breast cancer patients’ and survivors’ health-related quality of life.

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Asian Pacific Journal of Cancer Prevention
Volume 26, Issue 3
March 2025
Pages 715-723

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History

  • Receive Date: 07 September 2024
  • Revise Date: 22 January 2025
  • Accept Date: 12 March 2025

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