Incidence and Survival Trends of Cervical Cancer in Khon Kaen, Thailand

Pasane, Jakkree; Sriwatana, Kan; Krasairsom, Kuntawit; Suwunnapang, Napatsanun; Santong, Chalongpon; Chumworathayi, Bandit

doi:10.31557/APJCP.2025.26.4.1393

Incidence and Survival Trends of Cervical Cancer in Khon Kaen, Thailand

Document Type : Research Articles

Authors

¹ Department of Community Medicine, Faculty of Medicine, Khon Kaen University, Thailand.

² Cancer Registry Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand.

³ Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Thailand.

10.31557/APJCP.2025.26.4.1393

Abstract

Objective: To evaluate and report the incidence and survival trends of cervical cancer in Khon Kaen, Thailand, during 1991-2020. Methods: A retrospective study was conducted by using the electronic cancer registry database of Khon Kaen province population. Joinpoint regression model was used to analyze the Age-Standardized Incidence Rate (ASR) and the incidence trend graph was built. Overall Observed Survival (OS) was analyzed by Kaplan Meier method and the survival trend graph was built similarly. Result: During 1991-2020, 3,071 cervical cancer patients were found in Khon Kaen. Their mean age was 51.7 year-old. The ASR had decreased from 13.51 (95%CI: 10.67-16.35) per 100,000 women-year in 1991 to 7.63 (95%CI: 5.93-9.33) per 100,000 women-year in 2020. This trend was consistent with the country’s and international trends. The highest incidence was found in 1993, which was 17.73 (95%CI: 14.65-20.81), and the lowest incidence was found in 2016, which was 5.7 (95%CI: 4.30-7.10) per 100,000 women-year. However, the 5-year OS was 48.37% (95%CI: 46.49-50.22), which was a constant trend. At the beginning in 1991-1995, the OS was 40.31% (95%CI: 35.43-45.12), and at the end in 2016-2020, the OS was 40.46% (95%CI: 34.59-46.23). These were very similar. Conclusion: In Khon Kaen, Thailand, during 1991-2020, the cervical cancer incidence (ASR) trend was decreasing, while the cervical cancer survival (OS) trend was constant. WHO elimination of cervical cancer initiative target should be reached by 2030.

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